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Foto: Weizenkorn Triticum Karamyschevii Schwamlicum fotografiert von Ursula Schulz-Dornburg im Vavilov Institut zu St.Petersburg

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18.02.2021 |

EFSA: Risk assessment of New GE plants necessary even if no additional genes are inserted

European Food Safety Authority presents new report

18 February 2021 / The European Food Safety Authority (EFSA) has published another report on the risk assessment of plants developed with new genetic engineering (New GE). The report includes plants generated using gene scissor CRISPR/Cas applications where no new additional genes are inserted (so-called SDN-1 applications). The EFSA report shows that detailed risk assessment must be carried out even if no additional genes are inserted. The report is the outcome of a consultation which included Testbiotech.

The example chosen by EFSA is wheat, derived from application of CRISPR/Cas, with a strongly reduced gluten content. This protein is thought to trigger inflammatory responses. Using CRISPR/Cas meant that several dozen genes and gene copies in the wheat genome were changed at the same time. EFSA rightly concludes that these complex patterns of genetic change go beyond what has been achieved in genetic engineering and conventional breeding thus far. EFSA explained that if an application for market approval was filed, then risk assessment should take issues such as molecular changes, gene expression and the potential impact on health and the environment into account.

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